PHYSICIAN PRACTICE

Treatment of Uterine Fibroids should be tailored to the size and location of the tumors; the patient’s age, symptoms, desire to maintain fertility, and access to treatment; and the physician’s experience.

Treatment Options for UTERINE FIBROIDS

Uterine Fibroids

LIMITATION OF SURGICAL THERAPY

Hysterectomy

  • Morbidity
  • Risk of Surgical long-term complications
  • Complete loss of fertility

Myomectomy

  • Fibroid Recurrence
  • Potential uterian repture during
  • Pregnancy/delivery

Uterine-artery embolization (UAE)

  • Fibroid Recurrence
  • Pain
  • Possibility of severe complication
  • Possibility of subsequent hysterectomy in
    20% cases

Magnetic Resonance-guided Focused Ultrasound

  • High costs
  • Needs interventional radiologist
  • No sufficient data for fertility & subsequent
    pregnancies

LIMITATION OF MEDICAL THERAPY (HORMONAL)

NSAIDs

  • Lack of supportive evidence from clinical trials
  • GI side effects & risk of gastric ulceration

Anit fibrinolytics TNX

  • Can increase the size of myoma
  • TNX: tranexamic acid

Androgens (Danazol)

  • Cause acne hirsutism, edema
  • Associated with liver toxicity
  • Adverse effects on lipid metabolism & Wait gain

Aromatase Inhibitors (Al)

  • Causes hypoestrogenic side effects.
  • Insufficient evidence to support use of Al for Fibroid.

GNRH Agonist Leuprolide Triptorelin

  • Causes hot flushes, vaginal dryness & decreased libido
  • Increase bone mass loss; Increase risk of osteoporosis

Progestins

  • Breakthrough bleeding
  • Can increase size of myoma

Combined Oral Contraceptives (COC)

  • Breakthrough bleeding
  • Not safe for long term use
  • Can increase size of myama

TESTIMONIALS

For More Vidoes Watching Fibronorm Youtube Channel