Clinical study on effect of Tripterygium wilfordii Hook on uterine leiomyoma STUDY DESIGN: Randomized controlled Study. SUBJECT: 65 women with uterine fibroids TREATMENT: Tripterygium wilfordii DURATION: 6 months OUTCOMES: Decrease in volume of fibroids & Uterus, serum estradiol & progesterone
CONCLUSION
Tripterygium Wilfordii Hook may be an effective therapeutic agent for leiomyomas with fewer side effects Tripterygium Wilfordi Hook treatment showed a reversibly inhibitory effect on the ovary. It may be one of the mechanisms of Tripterygium Wilfordii Hook. in decreasing leiomyoma volume
CLINICAL EVIDENCE OF (EGCG 45%)
Treatment of symptomatic uterine fibroids with EGCG 45% a pilot randomized OBJECTIVE: To evaluate efficacy & safety of epigallocatechin gallate [EGCG] on UF burden and quality of life in women with symptomatic UF STUDY DESIGN : Double-blinded placebo-controlled randomized Study SUBJECT: 11 patients received 800mg of brown rice this one with treatment placebo group
TREATMENT: TREATMENT GROUP : 22 patients received 2 capsules of 400mg of green tea extract (45% EGCG) PLACEBO GROUP: 11 patients received 800mg of brown rice DURATION: 4 months OUTCOMES: Decrease in volume of fibroids, fibroid specific symptom severity, health related quality of life (HRQL), change in Hb
CONCLUSION
EGCG 45% shows promise as a safe and effective therapeutic agent for women with symptomatic UFs. Such a simple, inexpensive, and orally administered therapy can improve women’s health globally.
CLINICAL EVIDENCE OF VITAMIN D3
Vitamin D and the Risk of Uterine Fibroids.2 Donna Day Baird, Michael C. Hill, Joel M. Schectman and Bruce IN. Hollis STUDY DESIGN : Controlled Study SUBJECT RESULT: 674 women with uterine fibroid (459 Blacks, 215 whites) OUTCOMES: Association of Vitamin D with prevalence of uterine fibroid.
CONCLUSION
Sufficient vitamin D is associated with a reduced risk of uterine fibroids